Abstract:Since Sinian period,the strata of Guangdong Province have been well-developed. The lithostratigraphy and structural magma keep active,so the engineering characteristics of different layers of rocks and soils vary greatly. Based on the regional tectonics and practical engineering cases,the geological structural features and basic geotechnical characteristics of the main regions such as Zhujiang River Delta and Guangzhou City are discussed. If geotechnical problems are dealt with in the effective way with the cognition of regional geological structural conditions,and if macro- or micro- experience and lesson are adopted,large social benefit will be achieved.