Abstract: For fully representing the characteristics of fractured rock masses,such as strong nonhomogeneity and discontinuousness,the media are studied with generalized multiple porous media theory. Geological research and hydrogeologic tests show that,as main fractures and vertical passageway of aquifer,karstic collapse columns have hydrogeologic characteristics and calculation mode of seepage rate different from that of joints in rock masses and should be generalized as another kind of main fractures. So,the groundwater system of Fangezhuang mine is simulated accurately by generalized multiple porous media seepage model in which fault F0,Jingkou syncline axis,Tatuo syncline axis and No. 13 karstic collapse column are main fractures,sandstone of coal floor is the target aquifer,equivalent porous media are among main fractures,and groundwater flow is mainly controlled by main fractures and obeys cubic law,karstic collapse columns work as water pipelines,and the fractured rock masses are equivalent to porous media. The model well represents dimensional characteristics of fractured system of groundwater,especially for the strong runoff zone and local discontinuous seepage. Water volume of colliery is forecasted with the model,and the results show that storage capacity and permeability of normal fractured rock masses in sandstone aquifer are poor,and the mining water in mine is mainly from sandstone aquifer recharged by Ordovician limestone with vertical passageways or fractures. By analyzing seepage fields and taking dewatering volume of the colliery as input,the stimulation results show that the natural volume and the largest volume of groundwater on the third mining level are 0.167 m3/s and 0.25 m3s respectively,and the total natural volume and the largest total volume of groundwater of this mine are 0.333~0.417 m3/s and 0.5 m3/s respectively.