Abstract：By experiment setting that is developed by the authors and based on the theory of uniform design，uniform experimental study on permeable coefficient in 19 samples from the aquifer under high stress indicates that the permeable coefficient and effective stress can be expressed by damped exponential function. The study also shows that the regression coefficients are synthetically influenced by characteristic grains ， and ，and characteristic parameter and the porosity . Both the experimental study and the variance analysis identify that the value of permeable coefficient under zero stress is determined by n and ；and the effective influencing coefficient of stress is controlled by ， and ，especially by . The larger the value of is the smaller the values of and are，the larger the values of effective stress influencing coefficient are. This research points out that the law and value of permeable coefficient in deep aquifer can be predicted by characteristic grain，characteristic parameter，and effective stress of soil.
