Abstract：In order to investigate the macroscopic mechanics effects of chemical kinetics of water-rock interaction on the deformation and failure，the calcic rock，red sandstone and granite reacting chemically with different aqueous solution at atmospheric temperature and atmospheric pressure are uniaxially compressed. The quantitative results concerning the changes of uniaxially compressive strength under different conditions are obtained. The mechanical effects of water on rock are closely related to the chemical action of water-rock or the chemical damage in rock. The intensity of chemical damage is proportional to the intensity of chemical action in water-rock system. The mechanical effect of the chemical action of water on rock is time-dependent. The primary factors influencing chemical damage in rock consist of the chemical property of rock and aqueous solution，the structure or homogeneity of rocks，the flow velocity of aqueous solution passing through rock，and the cause of formation or evolution of rock.
