The paper summarizes and classifies basic geological condition and environmental factors of landslides and high slope disasters along Sanhui—Kaili Highway and analyzes the resulting mechanism，deformation mechanism and developing reason of different types of disasters. The paper expounds the design principle of geological disaster and also presents some stabilized measures adopted in engineering and their merits and shortcomings. Finally，the paper summarizes experience and lessons for preventing and controlling geological disasters during the construction of express highway.