Steel-tube bored grouting anti-sliding retaining wall is a technique of combining grouting with micropiles，which is treated as a retaining wall in mechanical analysis. The most significant feature is that steel-tube bored grouting anti-sliding retaining wall changes a part of sliding mass to anti-sliding mass. Taking the landslide K108 of Guangdong segment of Beijing—Zhuhai Expressway for example，the strata lithology，geologic structure and hydrogeologic feature of the landslide are introduced；and the five slip surfaces are found by displacement monitoring. The landslide is reinforced by steel-tube bored grouting anti-sliding retaining wall and discharging groundwater from sliding mass；the properties of rocks and soils in the landslide are checked by means of PS wave test and pressuremeter test. The landslide K108 is proved to be stable by means of analysis of monitoring displacement and stability computation. The results show that the steel-tube bored grouting anti-sliding retaining wall is an effective method for treating landslide.